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Methotrexate: Severe bone marrow suppression, aplastic anemia, and GI toxicity have been reported with concomitant NSAID therapy. Generic Relafen helps relieve pain and inflammation associated with rheumatoid arthritis and osteoarthritis. The 750 mg tablets also contain black iron oxide, red iron oxide, cod delivery nabumetone and yellow iron oxide. The trials were not designed to correlate symptoms and endoscopy scores.
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